Customize Consent Preferences

We use cookies to help you navigate efficiently and perform certain functions. You will find detailed information about all cookies under each consent category below.

The cookies that are categorized as "Necessary" are stored on your browser as they are essential for enabling the basic functionalities of the site. ... 

Always Active

Necessary cookies are required to enable the basic features of this site, such as providing secure log-in or adjusting your consent preferences. These cookies do not store any personally identifiable data.

No cookies to display.

Functional cookies help perform certain functionalities like sharing the content of the website on social media platforms, collecting feedback, and other third-party features.

No cookies to display.

Analytical cookies are used to understand how visitors interact with the website. These cookies help provide information on metrics such as the number of visitors, bounce rate, traffic source, etc.

No cookies to display.

Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors.

No cookies to display.

Advertisement cookies are used to provide visitors with customized advertisements based on the pages you visited previously and to analyze the effectiveness of the ad campaigns.

No cookies to display.

Home Type 1 Global prevalence of erectile dysfunction and its associated risk factors among men with type 1 diabetes: a systematic review and meta-analysis

Global prevalence of erectile dysfunction and its associated risk factors among men with type 1 diabetes: a systematic review and meta-analysis

by Zhirong Zhu
0 comments Donate
  • Lovic D, Piperidou A, Zografou I, Grassos H, Pittaras A, Manolis A. The growing epidemic of diabetes mellitus. Curr Vasc Pharm. 2020;18:104–9.

    Article 
    CAS 

    Google Scholar
     

  • Atkinson MA, Eisenbarth GS, Michels AW. Type 1 diabetes. Lancet. 2014;383:69–82.

    Article 
    PubMed 

    Google Scholar
     

  • Melendez-Ramirez LY, Richards RJ, Cefalu WT. Complications of type 1 diabetes. Endocrinol Metab Clin North Am. 2010;39:625–40.

    Article 
    PubMed 

    Google Scholar
     

  • Xu G, Liu B, Sun Y, Du Y, Snetselaar LG, Hu FB, et al. Prevalence of diagnosed type 1 and type 2 diabetes among US adults in 2016 and 2017: population based study. BMJ. 2018;362:k1497.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Yafi FA, Jenkins L, Albersen M, Corona G, Isidori AM, Goldfarb S, et al. Erectile dysfunction. Nat Rev Dis Prim. 2016;2:16003.

    Article 
    PubMed 

    Google Scholar
     

  • MacDonald SM, Burnett AL. Physiology of erection and pathophysiology of erectile dysfunction. Urol Clin North Am. 2021;48:513–25.

    Article 
    PubMed 

    Google Scholar
     

  • Chitaley K, Kupelian V, Subak L, Wessells H. Diabetes, obesity and erectile dysfunction: field overview and research priorities. J Urol. 2009;182:S45–50.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kouidrat Y, Pizzol D, Cosco T, Thompson T, Carnaghi M, Bertoldo A, et al. High prevalence of erectile dysfunction in diabetes: a systematic review and meta-analysis of 145 studies. Diabet Med. 2017;34:1185–92.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Brunner GA, Pieber TR, Schattenberg S, Ressi G, Wieselmann G, Altziebler S, et al. [Erectile dysfunction in patients with type I diabetes mellitus]. Wien Med Wochenschr. 1995;145:584–6.

    CAS 
    PubMed 

    Google Scholar
     

  • Azmi S, Ferdousi M, Alam U, Petropoulos IN, Ponirakis G, Marshall A, et al. Small-fibre neuropathy in men with type 1 diabetes and erectile dysfunction: a cross-sectional study. Diabetologia. 2017;60:1094–101.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Bacon CG, Hu FB, Giovannucci E, Glasser DB, Mittleman MA, Rimm EB. Association of type and duration of diabetes with erectile dysfunction in a large cohort of men. Diabetes Care. 2002;25:1458–63.

    Article 
    PubMed 

    Google Scholar
     

  • Caruso P, Cirillo P, Carbone C, Sarnataro A, Maiorino MI, Bellastella G, et al. Sexual dysfunctions and short-term glucose variability in young men with type 1 diabetes. Hormones. 2021;20:475–82.

    Article 
    PubMed 

    Google Scholar
     

  • Hylmarova S, Stechova K, Pavlinkova G, Peknicova J, Macek M, Kvapil M. The impact of type 1 diabetes mellitus on male sexual functions and sex hormone levels. Endocr J. 2020;67:59–71.

    Article 
    PubMed 

    Google Scholar
     

  • Dan A, Chakraborty K, Mondal M, Neogi R, Chatterjee S, Makhal M. Erectile dysfunction in patients with diabetes mellitus: its magnitude, predictors and their bio-psycho-social interaction: a study from a developing country. Asian J Psychiatr. 2014;7:58–65.

    Article 
    PubMed 

    Google Scholar
     

  • Fedele D, Bortolotti A, Coscelli C, Santeusanio F, Chatenoud L, Colli E, et al. Erectile dysfunction in type 1 and type 2 diabetics in Italy. On behalf of Gruppo Italiano Studio Deficit Erettile nei Diabetici. Int J Epidemiol. 2000;29:524–31.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kulecki M, Naskret D, Kaminski M, Kasprzak D, Lachowski P, Klause D, et al. Arterial stiffness and the non-dipping pattern in type 1 diabetes males with and without erectile dysfunction. Sci Rep. 2023;13:7265.

    Article 
    ADS 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Kaminski M, Kulecki M, Lachowski P, Kasprzak D, Kulczycka A, Kozlowska M, et al. Erectile dysfunction in individuals with Type 1 diabetes is associated with long-term metabolic control and diabetic complications: a cross-sectional study. Int J Angiol. 2022;31:97–106.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Nisahan B, Kumanan T, Rajeshkannan N, Peranantharajah T, Aravinthan M. Erectile dysfunction and associated factors among men with diabetes mellitus from a tertiary diabetic center in Northern Sri Lanka. BMC Res Notes. 2019;12:210.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Maiorino MI, Bellastella G, Della Volpe E, Casciano O, Scappaticcio L, Cirillo P, et al. Erectile dysfunction in young men with type 1 diabetes. Int J Impot Res. 2017;29:17–22.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Kalter-Leibovici O, Wainstein J, Ziv A, Harman-Bohem I, Murad H, Raz I, et al. Clinical, socioeconomic, and lifestyle parameters associated with erectile dysfunction among diabetic men. Diabetes Care. 2005;28:1739–44.

    Article 
    PubMed 

    Google Scholar
     

  • Klein R, Klein BE, Moss SE. Ten-year incidence of self-reported erectile dysfunction in people with long-term type 1 diabetes. J Diabetes Complicat. 2005;19:35–41.

    Article 

    Google Scholar
     

  • Pop-Busui R, Braffett BH, Wessells H, Herman WH, Martin CL, Jacobson AM, et al. Diabetic peripheral neuropathy and urological complications in Type 1 diabetes: findings from the epidemiology of diabetes interventions and complications study. Diabetes Care. 2022;45:119–26.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Van Cauwenberghe J, Enzlin P, Nefs G, Ruige J, Hendrieckx C, De Block C, et al. Prevalence of and risk factors for sexual dysfunctions in adults with type 1 or type 2 diabetes: results from Diabetes MILES – Flanders. Diabet Med. 2022;39:e14676.

    Article 
    PubMed 

    Google Scholar
     

  • Wang F, Dai S, Wang M, Morrison H. Erectile dysfunction and fruit/vegetable consumption among diabetic Canadian men. Urology. 2013;82:1330–5.

    Article 
    PubMed 

    Google Scholar
     

  • Turek SJ, Hastings SM, Sun JK, King GL, Keenan HA. Sexual dysfunction as a marker of cardiovascular disease in males with 50 or more years of type 1 diabetes. Diabetes Care. 2013;36:3222–6.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Georgescu O, Reghina A, Ioacara S, Fica S. Androgen deficiency, erectile dysfunction and chronic microvascular complications in male diabetic patients. Rom J Diabetes Nutr Metab Dis. 2013;20:401–7.

    CAS 

    Google Scholar
     

  • Jamieson F, Chalmers J, Duncan C, Prescott RJ, Campbell IW. Erectile dysfunction in type 1 diabetic males. Br J Diabetes Vasc Dis. 2008;8:232–4.

    Article 

    Google Scholar
     

  • Manalo TA, Biermann HD, Patil DH, Mehta A. The temporal association of depression and anxiety in young men with erectile dysfunction. J Sex Med. 2022;19:201–6.

    Article 
    PubMed 

    Google Scholar
     

  • Li H, Gao T, Wang R. The role of the sexual partner in managing erectile dysfunction. Nat Rev Urol. 2016;13:168–77.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Ayta IA, McKinlay JB, Krane RJ. The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences. BJU Int. 1999;84:50–56.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Nguyen HMT, Gabrielson AT, Hellstrom WJG. Erectile dysfunction in young men-a review of the prevalence and risk factors. Sex Med Rev. 2017;5:508–20.

    Article 
    PubMed 

    Google Scholar
     

  • Hunter CS, Stein RW. Evidence for loss in identity, de-differentiation, and trans-differentiation of Islet beta-Cells in Type 2 diabetes. Front Genet. 2017;8:35.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Rosen RC, Cappelleri JC, Smith MD, Lipsky J, Pena BM. Development and evaluation of an abridged, 5-item version of the International Index of Erectile Function (IIEF-5) as a diagnostic tool for erectile dysfunction. Int J Impot Res. 1999;11:319–26.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Maiorino MI, Bellastella G, Petrizzo M, Della Volpe E, Orlando R, Giugliano D, et al. Circulating endothelial progenitor cells in type 1 diabetic patients with erectile dysfunction. Endocrine. 2015;49:415–21.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Pajovic B, Dimitrovski A, Fatic N, Malidzan M, Vukovic M. Vacuum erection device in treatment of organic erectile dysfunction and penile vascular differences between patients with DM type I and DM type II. Aging Male. 2017;20:49–53.

    Article 
    PubMed 

    Google Scholar
     

  • Shamloul R, Ghanem H. Erectile dysfunction. Lancet. 2013;381:153–65.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Toschi E. Type 1 diabetes and aging. Endocrinol Metab Clin North Am. 2023;52:389–403.

    Article 
    PubMed 

    Google Scholar
     

  • Wessells H, Penson DF, Cleary P, Rutledge BN, Lachin JM, McVary KT, et al. Effect of intensive glycemic therapy on erectile function in men with type 1 diabetes. J Urol. 2011;185:1828–34.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Bortolotti A, Fedele D, Chatenoud L, Colli E, Coscelli C, Landoni M, et al. Cigarette smoking: a risk factor for erectile dysfunction in diabetics. Eur Urol. 2001;40:392–6.

    Article 
    CAS 
    PubMed 

    Google Scholar
     

  • Liu Q, Zhang Y, Wang J, Li S, Cheng Y, Guo J, et al. Erectile dysfunction and depression: a systematic review and meta-analysis. J Sex Med. 2018;15:1073–82.

    Article 
    PubMed 

    Google Scholar
     

  • Farooqi A, Gillies C, Sathanapally H, Abner S, Seidu S, Davies MJ, et al. A systematic review and meta-analysis to compare the prevalence of depression between people with and without Type 1 and Type 2 diabetes. Prim Care Diabetes. 2022;16:1–10.

    Article 
    PubMed 

    Google Scholar
     

  • Buchberger B, Huppertz H, Krabbe L, Lux B, Mattivi JT, Siafarikas A. Symptoms of depression and anxiety in youth with type 1 diabetes: a systematic review and meta-analysis. Psychoneuroendocrinology. 2016;70:70–84.

    Article 
    PubMed 

    Google Scholar
     

  • Ma K, Song P, Liu Z, Yang L, Wang L, Zhou J, et al. Genetic evidence suggests that depression increases the risk of erectile dysfunction: a Mendelian randomization study. Front Genet. 2022;13:1026227.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Rawshani A, Sattar N, Franzen S, Rawshani A, Hattersley AT, Svensson AM, et al. Excess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study. Lancet. 2018;392:477–86.

    Article 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • Hietala K, Harjutsalo V, Forsblom C, Summanen P, Groop PH, FinnDiane Study G. Age at onset and the risk of proliferative retinopathy in type 1 diabetes. Diabetes Care. 2010;33:1315–9.

    Article 
    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • You may also like

    Today’s Diabetes News, your ultimate destination for up-to-date and insightful information on diabetes, health tips, and living a fulfilling life with diabetes. Our mission is to empower and support individuals with diabetes, their loved ones, and the wider community by providing reliable, relevant, and engaging content that fosters a healthier and happier life.

    Most Viewed Articles

    Latest Articles

    Copyright MatchingDonors.com©️ 2025 All rights reserved.

    Are you sure want to unlock this post?
    Unlock left : 0
    Are you sure want to cancel subscription?
    -
    00:00
    00:00
      -
      00:00
      00:00