Association between disease risk and change in body mass index (BMI) or glycated hemoglobin (HbA1c). Source: Diabetes, Obesity, and Metabolism (2024). DOI:10.1111/dom.15896
A research team from the Cleveland Clinic has published the first study to evaluate the independent, real-world impact on clinical outcomes of weight loss and glycemic control in patients with type 2 diabetes treated with antidiabetic medications, specifically GLP-1RAs (a class of drugs that includes Ozempic and Wegovy).
The study found that every 1% reduction in BMI was associated with a 4% reduction in cardiovascular disease risk, regardless of changes in blood glucose levels. Furthermore, blood glucose control was associated with a lower risk of chronic kidney disease, regardless of changes in weight. These results are clinically relevant and highlight the importance of treating patients with type 2 diabetes in terms of both blood glucose control and obesity.
Retrospective findings showed that Published in Diabetes, Obesity, and Metabolismused de-identified data from electronic health records of more than 1,300 patients with type 2 diabetes evaluated at the Cleveland Clinic.
More information:
Anukriti Sharma et al. “Elucidating the role of weight loss and glycemic control in type 2 diabetes patients” Diabetes, Obesity, and Metabolism (2024). DOI: 10.1111/dom.15896
Citation: Study Evaluates Impact of Weight Loss and Blood Glucose Control in Type 2 Diabetes (September 18, 2024) Retrieved September 23, 2024 from https://medicalxpress.com/news/2024-09-impact-weight-loss-blood-sugar.html
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