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Mounjaro (tirzepatide) is a once-weekly injection that helps people with type 2 diabetes manage their blood sugar levels.
it was first approved Approved by the U.S. Food and Drug Administration (FDA) in 2022, it is quickly becoming popular for facilitating diabetes management.
One of the side effects of drugs is weight loss. So, can Munjaro help you lose weight? This article explains everything you need to know.
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What is Munjaro?
Mounjaro is the first drug in a class of drugs known as GIP/GLP-1 receptor agonists. It is approved by the FDA to improve blood sugar control in people with type 2 diabetes, along with a healthy diet and exercise.
Want to know more? Read: Everything you need to know about Munjaro.
Can Munjaro help you lose weight?
yes. And in fact, the FDA approved a weight loss drug called Zepbound based on clinical studies that support this work. (Zepbound is the same drug as Munjaro, which has the same strength, but has a different name for use as a weight loss treatment.)
FDA approval of this drug was primarily based on: Results of two tests.
Both studies evaluated the drug’s effectiveness for weight loss and maintenance, along with a reduced-calorie diet and increased physical activity, in overweight or obese adults with at least one weight-related disease. did.
The trial looked at outcomes after taking the drug at doses of either 5mg, 10mg, or 15mg once a week for 72 weeks. At the end of the study period, participants who received any dose of drug therapy lost significantly more weight than those who received a placebo (inactive treatment).
See below for more information. Munjaro Dosage Guide: How Much Should I Take?
How much weight will I lose by taking Mounjaro/Zepbound?
The large trial involved adults without diabetes. His average starting weight was 231 pounds (105 kilograms), and his average body mass index (BMI, a measure of weight in relation to height) was 38. Patients receiving 15 mg, the highest approved dose, lost an average of 18% of their body weight. Percentage of body weight compared to patients taking placebo.
In the second study, adults with type 2 diabetes had an average starting weight of 222 pounds (101 kilograms) and an average BMI of 36. At the end of the study, those who took 15 milligrams of the drug weighed, on average, 12 percent less than those who took a placebo.
Who should not take this medicine?
Take these medications only if prescribed by your doctor.
Mounjaro is approved by the FDA to treat patients with type 2 diabetes. Zepbound is approved to treat adults who are obese (BMI 30 or higher) or overweight (BMI 27 or higher) with at least one weight-related disease (such as type 2 diabetes, high blood pressure, or high cholesterol).
Mounjaro is not FDA-approved for patients with type 1 diabetes, but if you have high blood sugar levels and low insulin sensitivity, your doctor may use it off-label (in a manner not officially approved by the FDA). We may suggest that you use it.
See below for more information. Can I take Munjaro if I have type 1 diabetes?
Neither drug is recommended for pregnant women. If you are pregnant or planning to become pregnant, you should talk to your healthcare provider and stop the medicine.
Do not use either drug if you or someone in your family has had medullary thyroid cancer (MTC) or if you have multiple endocrine neoplasia syndrome type 2 (MEN 2).
Do not use Mounjaro or Zepbound if you are allergic to tirzepatide or any other ingredients in the medicine.
Before you start treatment with these drugs, tell your doctor about all the medicines you use.
Please refer to. prescribe information Learn more about Mounjaro and Zepbound, who should use these drugs, and who should avoid them.
Learn about the potential side effects below. Munjaro side effects.
Can I take Mounjaro or Zepbound and other medications at the same time?
This depends on other medications you are taking.
Generally, Munjaro and Zepbound can be taken with medications such as metformin and insulin if all medications are prescribed at the same time. Always inform your health care provider about all medicines you are taking.
Do not use Munjaro with GLP-1 drugs. GLP-1 receptor agonists include:
Additionally, Mounjaro should not be used with DPP-4 inhibitors. These include:
- Sitagliptin (Januvia)
- Saxagliptin (Onglyza)
- Linagliptin (Tragenta)
- Alogliptin (Nesina)
If you are unsure about how a medication you are taking may interact with a new medication you are considering taking, be sure to consult your doctor.
How much should I take for weight loss?
Mounjaro is not explicitly approved for weight loss by the FDA, so there is no recommended dosage for weight loss.
For Zepbound, available doses are 2.5 mg, 5 mg, 10 mg, and 15 mg, taken by injection once a week. Maximum dose is 15 mg.
Talk to your doctor if you want to lose weight. In addition to Zepbound, there are other diabetes treatments specifically approved by the FDA for weight loss.
read more: Munjaro Dosing Guide.
How long does it take to lose weight with Munjaro?
Even if you hire Mr. Munjaro’s weight loss diet partner, Mr. Sepbound, success will not happen overnight.
If you lose weight while taking Zepbound, you may also need to make lifestyle changes, such as changing your diet and increasing your physical activity.
Many studies examining Zepbound’s effectiveness on weight loss were conducted over many months, and the trial used as the basis for FDA approval lasted almost a year and a half.
Talk to your doctor if you want to lose weight. They can provide recommendations for sustained and permanent weight loss.
Why am I not losing weight on Mounjaro or Zepbound?
If you are not losing weight after taking this medication, there are several common causes.
you may I just hit As your body’s metabolism slows and adapts to the new set point, you enter a plateau in weight loss. Over time, you may start losing weight again.
You may not be taking the recommended dose. Or you may not have made enough lifestyle changes to support the weight loss promoted by the drug.
Also, for some people, this drug may not be an effective tool for weight loss or weight management. Not all medicines work for everyone.
Which is better for weight loss: Ozempic or Munjaro?
Ozempic and Munjaro’s weight loss product, Zepound, both work similarly and help you lose weight.
Ozempic is not approved by the FDA as a weight loss drug, but both drugs suppress appetite and slow digestion.
Additionally, both drugs help stabilize blood sugar levels. Therefore, many people lose weight when taking either one.
but, recent research Mounajaro/Zepbound has been shown to cause more weight loss than Ozempic in obese people.
average trial participant I lost an additional 12 pounds. When taking Munjaro/Zepbound over Ozempic at a maximum weekly dose of 15 mg.
Learn more about how these medicines compare below. Ozempic vs. Munjaro: Which one should you choose?
Can I take Mounjaro or Zepbound if I don’t have diabetes?
Mounjaro is approved by the FDA only for patients with type 2 diabetes. However, Zepbound is approved for overweight or obese adults with at least one of their weight-related conditions.
Additionally, many drugs for blood sugar control and weight loss are prescribed by doctors off-label.
If your doctor thinks you are a candidate for Munjaro, he or she may prescribe off-label medicines to treat symptoms such as:
Never take any medication that has not been prescribed for you, and consult your doctor before starting any medication.
final thoughts
Mounjaro represents a significant advance in the treatment and weight management of type 2 diabetes. Its recent FDA approval under the brand name Zepbound for weight loss underscores its effectiveness in this area.
As with other diabetes medications, it is important to use Mounjaro (and Zepbound) carefully, considering dosage requirements and potential side effects, and under medical supervision.
Individual reactions may vary, so it is important to discuss with your health care team whether these medications are compatible with your individual health needs.
We recommend the following articles: Everything you need to know about Munjaro.
