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How type 2 diabetes increases risk

by Eileen Bailey
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Monitoring your type 2 diabetes may reduce your risk of Alzheimer’s disease.Rich Leg/Getty Images
  • Researchers report that there is evidence to suggest that there is a link between type 2 diabetes and the risk of Alzheimer’s disease, which some medical professionals refer to as type 3 diabetes.
  • They said that eating a high-fat diet can lead to higher levels of inflammation, which can increase the risk of dementia.
  • They point out that eating a healthy diet and participating in a healthy lifestyle may reverse the process and reduce the risk of developing Alzheimer’s disease.

There is growing evidence that type 2 diabetes and Alzheimer’s disease are linked, according to research completed at Texas A&M University and presented at an international conference. annual meeting of the American Society for Biochemistry and Molecular Biology.

among them findingsAlthough it has not yet been published in a peer-reviewed journal, the researchers used mice in their experiments to examine the relationship between the two diseases.

Scientists said they tracked specific proteins in the gut to see how they affect brain processes. They reported that eating a high-fat diet suppresses a protein called jak3.

Mice without this protein developed inflammation that started in the intestines and progressed to the liver and brain. These mice developed Alzheimer’s disease-like symptoms, including cognitive impairment.

Researchers suggest that managing or avoiding type 2 diabetes may reduce the risk of Alzheimer’s disease.

The researchers note that previous studies have shown that diet influences the onset and severity of diabetes and, more recently, has been implicated in the risk of developing Alzheimer’s disease.

meta-analysis data It has been demonstrated that people with type 2 diabetes have a 56 percent increased risk of Alzheimer’s disease dementia. ” narendra kumarsaid lead author of the study and associate professor of pharmacy at Texas A&M. Today’s medical news. “We believe that diet and lifestyle may be some of the key factors contributing to the progression of Alzheimer’s disease, as there is a known association between diet and lifestyle in type 2 diabetes. I am thinking about it.”

Although the study did not examine this association and it is too early to draw any conclusions, Kumar believes the association may be similar for other types of dementia.

Texas A&M researchers have found that the jak3 protein can cause leaky gut, which can lead to low-grade chronic inflammation, type 2 diabetes, a decreased ability of the brain to clear toxins, and dementia-like symptoms. He says he has learned. .

Leaky gut is a condition in which there are gaps in the intestinal wall that allow toxins and bacteria to leak from the intestines into the bloodstream. Not all medical professionals recognize this as a distinct medical condition, so more research is needed.

Researchers believe it is possible to stop this process, which involves inflammation, by eating a healthy diet and controlling blood sugar levels.

They say that ideally, healthy eating and lifestyle habits can be started early enough to avoid hyperglycemia and at least early enough to reverse prediabetes. Ta.

Scientists suggest that these changes may reduce the risk of type 2 diabetes and Alzheimer’s disease.

According to some researchers, about 81% of people with Alzheimer’s disease also have type 2 diabetes. Report by USC Keck School of Medicine.

The risk of dementia is consistent with a diagnosis of diabetes, and the younger a person is at developing diabetes, the greater the risk of developing dementia.

Some scientists refer to the association of these two diseases as “type 3 diabetes.”

Because the liver metabolizes food, researchers say it may be important for the gut-brain connection.

Although it is still unclear why this condition exists, experts know that high blood sugar and insulin can have negative effects on the brain and increase the risk of Alzheimer’s disease. alzheimer’s disease association.

The brain is the most energy-hungry organ and requires half of the body’s sugar energy to function properly. According to , both high and low blood sugar can damage blood vessels in the brain. Centers for Disease Control and Prevention.

When blood sugar levels are out of the normal range, they can damage nerves and blood vessels in the brain and cause problems with memory, learning, mood, weight gain, and hormonal changes. Over time, it can cause Alzheimer’s disease.

According to , the goal of treating type 2 diabetes is to prevent it from developing other health problems. National Institutes of Health.

“Severe obesity is fatal. The human body can grow 10 to 20 years older than your actual age. Heart disease is the biggest cause of death,” he said. Dr. Mitchell Roslinchief of bariatric surgery at Northwell Lenox Hill Hospital in New York, was not involved in the study.

Roslin says there are several effective treatments.

“Bariatric surgery is a tool that allows you to eat less, eat healthier foods, and be more active,” Roslin said. Today’s medical news. “It will still be influenced by socio-economic factors, the environment and the stresses people face.”

He added that over the past few years, federal regulators have approved several weight-loss drugs that help reduce the risk of diabetes. Tirzepatide (Mounjaro, Zepbound) and semaglutide (Ozempic, Wegovy) reduce hunger, help you lose weight, and help control type 2 diabetes.

Diet, exercise and other lifestyle factors are also important, experts say.

“Dietary and lifestyle changes to address weight can be very effective in reducing and controlling diabetes risk,” he said. Lauren SepeShe is a clinical nutritionist at the Kellman Wellness Center in New York, but was not involved in the study. “While the advent of these new and more effective medications is very helpful for many people, there is also a lot you can do yourself to manage your symptoms.”

“We recommend a diet that is low in carbohydrates and sugar, as well as a diet that addresses inflammation,” Sepe said. Today’s medical news.

Sepe offered these tips:

  • Focus on lean protein, free-range protein, wild-caught fish, and seafood
  • Grass-fed meat in moderation. Grass-fed meat has been shown to contain more naturally anti-inflammatory omega-3 fatty acids compared to conventional meat, which is higher in omega-6 fatty acids, which promote inflammation. Masu.
  • Healthy fats found in olive oil, coconut oil, avocado, and more
  • These vegetables tend to have a high carbohydrate content, so eat plenty of non-starchy vegetables.
  • egg
  • Eat nuts and seeds in moderation. Although they are nutritious and contain healthy fats, they tend to be high in calories.
  • Consume moderate amounts of low-sugar fruits such as apples, citrus fruits, berries, and melons.
  • Dairy products in moderation, preferably high-quality organic versions

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