Prof. Kei Sakamoto on exercise, AMPK and glucose uptake in type 2 diabetes
Watch the video on YouTube to see EASD TV host speak with Prof. Kei Sakamoto, 12th recipient of the EASD – Novo Nordisk Foundation Diabetes Prize for Excellence, about his research into exercise, glucose uptake and insulin signalling.
The conversation explores how exercise stimulates glucose uptake in muscle, including the role of LKB1 and AMPK in pathways that function independently of insulin. Prof. Sakamoto discusses how understanding these mechanisms could inform new treatment approaches, particularly for people who cannot exercise as much as they would like, and why carefully targeting specific molecules and tissues is important.
He also reflects on the complexity of diabetes, the challenges of developing treatments that maintain the body’s metabolic balance, and the importance of fundamental research in paving the way for future discoveries.
Explore Prof. Kei Sakamoto’s portrait.
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