Beta

Collection of raw scRNA-seq data For the human islets datasets, raw scRNA-seq FASTQ files (10X Genomics) were downloaded from the Human Pancreas Analysis Program (HPAP) portal (https://hpap.pmacs.upenn.edu) (Table S1). HPAP-young and …

Researchers from the University of Florida’s Diabetes Institute have found an important clue for why the body’s immune system destroys insulin-producing cells in the pancreas, which leads to Type 1 …

Allo-Evasion™ 5.0-engineered iPSC beta islets are designed to overcome immune rejection and provide durable glucose control without chronic immunosuppressionCompelling preclinical data demonstrate rapid reversal of diabetes and sustained normoglycemia, human …

Type 1 diabetes is caused by an insufficient production of the hormone insulin by cells in the pancreas called beta cells and estimated to affect 9.5 million people worldwide. Low …

In the short term, glucose homeostasis increases, but long-term fasting during adolescence can impair beta-cell maturation. study: Chronic intermittent fasting impairs beta cell maturation and function in adolescent mice. Image …

Sana Biotechnology Announces Positive Clinical Results in Type 1 Diabetes Study of Pancreatic Islet Cell Transplantation Without Immunosuppression Released by Sana.com on January 7, 2025. Sana Biotechnology, Inc., a company …

Approximately 8 million people worldwide have type 1 diabetes (T1D). It is a chronic autoimmune disease in which the body attacks and destroys its own insulin-producing beta cells (pronounced “beta”) …

AAV8-mediated Mettl3 overexpression in NOD mouse β cells in vivo delays T1D progression. credit: natural cell biology (2024). DOI: 10.1038/s41556-024-01368-0 Approximately 8 million people worldwide have type 1 diabetes (T1D). …