gene

Collection of raw scRNA-seq data For the human islets datasets, raw scRNA-seq FASTQ files (10X Genomics) were downloaded from the Human Pancreas Analysis Program (HPAP) portal (https://hpap.pmacs.upenn.edu) (Table S1). HPAP-young and …

An immunofluorescence image of pancreatic cells (green) and immune cells (blue) in mice. UW researchers found that deleting a single stress-response gene in insulin-producing cells in the pancreas protects mice …

Credit: Unsplash/CC0 Public Domain A new gene therapy approach aimed at protecting people with type 1 diabetes from developing diabetic kidney disease—a serious and common complication of the condition, has …

In type 1 diabetes, insulin-producing beta cells (orange, lower left) in the pancreas (upper left) send out signals called exosomes (yellow dots). Immune sentinels called dendritic cells (large whitish cell, …

     For more than a decade, the Bashir family had no idea why their daughter Tania was born without a pancreas. Now, after years of testing, genomics researchers finally found …