trials

NatureLab-made islet cell implants sail through diabetes trials, but are they ready yet?First-in-human studies provide hope that islet replacement therapies derived from stem cells will prove safe and effective in …

Eslam Montaser, Sebastián E Abad, Viral N ShahThe Journal of Clinical Endocrinology & Metabolism, Volume 110, Issue 12, December 2025, Pages e4182–e4187https://doi.org/10.1210/clinem/dgaf211 Abstract Context The glucose management indicator (GMI) is …

(Reuters) -Eli Lilly said on Wednesday its experimental pill, orforglipron, helped reduce blood sugar levels in two late-stage trials. The oral drug is designed to mimic the appetite-suppressing GLP-1 hormone …

According to a clinical trial led by researchers at the Johns Hopkins Bloomberg School of Public Health, a modified version of the diet known to lower blood pressure, is also …

Patient's temperament From November 2019 to July 2023, 428 participants were registered at eight UK centres and randomized under a controlled diet (n = 211; Standard energy content, 2,000 kcal …

Design This study uses a hybrid type I effectiveness-implementation trial design [26] to test the effectiveness of LISTEN in a two-arm pragmatic, individual-level randomised controlled trial (RCT). We will simultaneously …

Introduction Diabetes mellitus (DM) is a chronic progressive disease with a high risk of comorbid physical and mental health problems (1). Lower glycated haemoglobin (HbA1c) is helpful in reducing the …