Nathan, D. M. The diabetes control and complications trial/epidemiology of diabetes interventions and complications study at 30 years: overview. Diabetes Care 37, 9–16 (2014).
Google Scholar
Thabit, H. et al. Home use of an artificial beta cell in type 1 diabetes. N. Engl. J. Med. 373, 2129–2140 (2015).
Google Scholar
Keenan, H. A. et al. Residual insulin production and pancreatic ß-cell turnover after 50 years of diabetes: Joslin Medalist Study. Diabetes 59, 2846–2853 (2010).
Google Scholar
Shapiro, A. M. J. et al. International trial of the Edmonton protocol for islet transplantation. N. Engl. J. Med. 355, 1318–1330 (2006).
Google Scholar
Reichman, T. W. et al. Stem cell-derived, fully differentiated islets for type 1 diabetes. N. Engl. J. Med. https://doi.org/10.1056/NEJMoa2506549 (2025).
Google Scholar
Wang, S. et al. Transplantation of chemically induced pluripotent stem-cell-derived islets under abdominal anterior rectus sheath in a type 1 diabetes patient. Cell 187, 6152–6164 (2024).
Google Scholar
Herold, K. C. et al. An anti-CD3 antibody, teplizumab, in relatives at risk for type 1 diabetes. N. Engl. J. Med. 381, 603–613 (2019).
Google Scholar
Ziegler, A. G. et al. Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children. JAMA 309, 2473–2479 (2013).
Google Scholar