Grains, oats are associated with higher risk

• Type 1 diabetes is a complex disease with autoimmune influences, and genetic factors often play a role in the risk.
• Researchers are interested in discovering what additional risk factors contribute to the development of type 1 diabetes.
• Recent research suggests that eating more of certain foods, such as oats, gluten-containing cereals, and fruit, may increase your risk of type 1 diabetes.
• In contrast, eating more of certain vegetables may reduce your risk of type 1 diabetes.

type 1 diabetes It affects children and adults, but often begins in young adulthood or earlier. Researchers are interested in understanding what factors contribute to its development. One area of ​​interest is how diet influences the development of type 1 diabetes.

This study investigated how certain foods are linked to the development of type 1 diabetes. Researchers were able to study the diets of more than 5,000 children who are genetically predisposed to type 1 diabetes.

When looking at all foods combined, oats, gluten-containing cereals, and fruit were associated with an increased risk of type 1 diabetes-related endpoints, while cruciferous vegetables were associated with a decreased risk. The results may prompt further research into how diet plays a role in the development of type 1 diabetes.

Type 1 diabetes is a type of diabetes that has different risk factors than type 2 diabetes. One significant risk factor is having a family history of type 1 diabetes.

Dr. Rebecca HicksA board-certified pediatric endocrinologist and medical director at Memorial Care Miller Children's and Women's Hospital Long Beach Endocrinology and Diabetes Center in Long Beach, California, who was not involved in the recent study, said: Explained. Today's medical news that:

“Type 1 diabetes occurs most frequently in individuals with a family history of type 1 diabetes, thyroid disease, or a genetic predisposition to autoimmune diseases such as celiac disease, and this risk is influenced by environmental factors such as enteroviruses. It is thought that a viral infection can 'unleash' this latent genetic risk and, over time, the individual will develop type 1 diabetes. ”

Type 1 diabetes is associated with the following symptoms: autoimmune reaction This is because the body's immune system affects the beta cells of the pancreas. Beta cells are located in: Island of Langerhans in the pancreas.

Researchers are interested in understanding what factors contribute to autoimmune responses and the development of type 1 diabetes.

As this recent study points out, one area of ​​research that has received little attention is how early childhood diet may influence pancreatic autoimmune responses and type 1 diabetes. That's what it means.

However, Professor Hicks said: “Previous studies examining associations with children's dietary intake patterns have shown an increased risk of type 1 diabetes associated with conditions such as: . Previous introduction — Before 3 months of age compared to 4 to 6 months of age — Higher intake of cereals, gluten, fruit, bananas, and milk. In addition to delaying the introduction of solids; [children over] He is 6 months old. ”

At the same time, she added, “eat more cruciferous vegetables (broccoli, Brussels sprouts, cauliflower, cabbage, kale) and berries.” [has] was done related to risk reduction”

The researchers who conducted this study wanted to examine the relationship between specific food choices and the development of type 1 diabetes. Through their data collection, they were able to examine 34 food groups.

They considered several different endpoints, including type 1 diabetes, islet cell antibodies and biochemical islet autoimmunity, and multiple biochemical islet autoimmunities.

The endpoint of islet autoimmunity refers to the body's autoimmune response that leads to the destruction and dysfunction of the pancreatic beta cells.

All participants were genetically predisposed to developing type 1 diabetes. The researchers measured dietary intake by repeatedly recording food for three days starting when the participants were three months old.

Over the data collection period, 94 participants developed type 1 diabetes, 247 developed islet cell antibodies and biochemical islet autoimmunity, and 206 developed multiple biochemical islet autoimmunities. 64 people experienced “progression from islet autoimmunity to type 1 diabetes.”

The researchers used both single-food and multiple-food models in their analyses. They were able to adjust for factors such as gender and familial diabetes. Therefore, they identified foods that were associated with increased or decreased risk of type 1 diabetes-related endpoints.

For example, they found that oats and bananas were associated with biochemical islet autoimmunity in addition to islet cell antibodies. Oats, bananas, fermented dairy products, and wheat were associated with multiple biochemical islet autoimmunities.

but, cruciferous vegetables Foods like broccoli and cauliflower were associated with a lower risk of these islet autoimmune endpoints. Rye, oats, and fruit were associated with an increased risk of type 1 diabetes, and berries were associated with a decreased risk.

Looking at all foods together, the study authors found that eating more cruciferous vegetables was associated with a lower risk of several type 1 diabetes-related endpoints, including oats, gluten-containing cereals, and They concluded that eating more fruit increased the risk.

Commenting on the study results, Hicks said:

“This study builds on previous related studies by showing an increased risk of type 1 diabetes associated with increased dietary intake of gluten-containing cereals, oats, rye, bananas, and fruit. It has also been shown that higher intakes of cruciferous vegetables and fruits reduce the risk. Restricting child food intake too much can lead to nutritional deficiencies, and research has shown no clear benefit to eliminating dietary categories altogether, however. There may be some benefits to increasing your intake of cruciferous vegetables and fruits as part of your diet.

Because the study has not yet been published in a peer-reviewed journal, full details of the study are not available to the public at this time, making it difficult to discuss the study's limitations.

Nevertheless, some potential limitations stand out. First, data on children's diets can be difficult to collect, and the data researchers were able to analyze relied on parent reports.

Additionally, the DIPP study only included Finnish participants, so caution should be taken when generalizing the results. Even though the researchers took into account factors such as energy intake and familial diabetes, unknown factors may have influenced the results.

The study authors believe that future research could help confirm that food choices can influence the autoimmune processes that lead to the development of type 1 diabetes, or verify that they do not. It is pointed out that there is a sex.

Suvi M. Virtanen MD, PhDsaid one of the study authors, a research professor at the Finnish Institute of Health and Welfare. MNT:

“Our study strongly suggests that diet is important in the development of type 1 diabetes. Of course, our findings need to be confirmed by other studies. We cannot provide dietary guidelines to prevent diabetes. […] We need to examine what factors in these commonly eaten nutritionally important foods are associated with increased disease risk. [For example]are environmental toxins having an effect? Confirmation of the results from other studies is also needed. ”

Dr. Daniel Ganjian, FAAPa board-certified pediatrician at Providence St. John's Health Center in Santa Monica, Calif., who was not involved in the study, pointed to several potential research avenues that could be useful in the future.